MARC details
000 -LEADER |
fixed length control field |
nab a22 7a 4500 |
001 - CONTROL NUMBER |
control field |
59836 |
003 - CONTROL NUMBER IDENTIFIER |
control field |
MX-TxCIM |
005 - DATE AND TIME OF LATEST TRANSACTION |
control field |
20191122160953.0 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
181108s2018||||ohu|||p|op||||00||0|eng|d |
024 8# - OTHER STANDARD IDENTIFIER |
Standard number or code |
https://doi.org/10.1021/acs.jnatprod.8b00486 |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
MX-TxCIM |
041 ## - LANGUAGE CODE |
Language code of text/sound track or separate title |
eng |
100 1# - MAIN ENTRY--PERSONAL NAME |
Personal name |
Helaly, S.E. |
9 (RLIN) |
8155 |
245 1# - TITLE STATEMENT |
Title |
Nematicidal cyclic lipodepsipeptides and a xanthocillin derivative from a phaeosphariaceous fungus parasitizing eggs of the plant parasitic nematode Heterodera filipjevi |
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) |
Name of publisher, distributor, etc. |
American Chemical Society, |
Date of publication, distribution, etc. |
2018. |
Place of publication, distribution, etc. |
Ohio, U.S. : |
500 ## - GENERAL NOTE |
General note |
Peer review |
520 ## - SUMMARY, ETC. |
Summary, etc. |
The new cyclic lipodepsipeptide ophiotine (1), two new arthrichitin derivatives named arthrichitins B (4) and C (5), a new xanthocillin-like alkaloid, xanthomide Z (2), and the previously described arthrichitin (3) were isolated from the liquid culture broth of a nematode-associated fungus with affinities to the genus Ophiosphaerella. The structural elucidation and determination of the absolute configuration of the new molecules were accomplished using a combination of spectroscopic and chemical techniques, including 1D and 2D NMR, HRMS, and Marfey's analysis. Opiotine (1) displayed moderate nematicidal activity against the host nematode (Heterodera filipjevi), while xanthomide Z (2) exhibited very weak activity. Arthrichitin C (5) showed very weak cytotoxic effects on several cancer cell lines, with IC50 values in the range of 24-33 ?M. Xanthomide Z is among few xanthocillin derivatives that comprise formamide functions instead of the cyano functions that are usually observed in this class of fungal alkaloids. |
546 ## - LANGUAGE NOTE |
Language note |
Text in English |
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Source of heading or term |
AGROVOC |
9 (RLIN) |
5669 |
Topical term or geographic name as entry element |
Disease control |
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Source of heading or term |
AGROVOC |
9 (RLIN) |
4804 |
Topical term or geographic name as entry element |
Plant nematodes |
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
9 (RLIN) |
1796 |
Topical term or geographic name as entry element |
Heterodera |
Source of heading or term |
AGROVOC |
700 1# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Ashrafi, S. |
9 (RLIN) |
419 |
700 1# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Teponno, R.B. |
9 (RLIN) |
8156 |
700 1# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Bernecker, S. |
9 (RLIN) |
8157 |
700 1# - ADDED ENTRY--PERSONAL NAME |
9 (RLIN) |
874 |
Personal name |
Dababat, A.A. |
Miscellaneous information |
Global Wheat Program |
Field link and sequence number |
INT2918 |
700 1# - ADDED ENTRY--PERSONAL NAME |
9 (RLIN) |
190 |
Personal name |
Maier, W. |
700 1# - ADDED ENTRY--PERSONAL NAME |
9 (RLIN) |
5109 |
Personal name |
Stadler, M. |
773 0# - HOST ITEM ENTRY |
Title |
Journal of Natural Products |
Related parts |
v. 81, no. 10, p. 2228-2234 |
International Standard Serial Number |
0163-3864 (Print) 1520-6025 (Online) |
856 4# - ELECTRONIC LOCATION AND ACCESS |
Uniform Resource Identifier |
https://libcatalog.cimmyt.org/Download/cis/59836.pdf |
Link text |
Access only for CIMMYT Staff |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Koha item type |
Article |
Suppress in OPAC |
No |
Source of classification or shelving scheme |
Dewey Decimal Classification |