MARC details
| 000 -LEADER |
|---|
| fixed length control field |
03535nab a22004097a 4500 |
| 001 - CONTROL NUMBER |
|---|
| control field |
56864 |
| 003 - CONTROL NUMBER IDENTIFIER |
|---|
| control field |
MX-TxCIM |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
|---|
| control field |
20211006085122.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
|---|
| fixed length control field |
ta |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
|---|
| fixed length control field |
150424s2015 xxu|||p|op||| 00| 0 eng d |
| 024 8# - OTHER STANDARD IDENTIFIER |
|---|
| Standard number or code |
https://doi.org/10.1007/s00122-015-2475-3 |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
MX-TxCIM |
| 041 ## - LANGUAGE CODE |
|---|
| Language code of text/sound track or separate title |
eng |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Suwarno, W.B. |
| 9 (RLIN) |
714 |
| 245 10 - TITLE STATEMENT |
|---|
| Title |
Genome‑wide association analysis reveals new targets for carotenoid biofortification in maize |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) |
|---|
| Place of publication, distribution, etc. |
New York: |
| Name of publisher, distributor, etc. |
Springer, |
| Date of publication, distribution, etc. |
2015. |
| 500 ## - GENERAL NOTE |
|---|
| General note |
Peer review |
| 500 ## - GENERAL NOTE |
|---|
| General note |
Open Access |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
Key message Genome-wide association analysis in CIMMYT’s association panel revealed new favorable native genomic variations in/nearby important genes such as hydroxylases and CCD1 that have potential for carotenoid biofortification in maize. Abstract Genome-wide association studies (GWAS) have been used extensively to identify allelic variation for genes controlling important agronomic and nutritional traits in plants. Provitamin A (proVA) enhancing alleles of lycopene epsilon cyclase (LCYE) and β-carotene hydroxylase 1 (CRTRB1), previously identified through candidate-gene based GWAS, are currently used in CIMMYT’s maize breeding program. The objective of this study was to identify genes or genomic regions controlling variation for carotenoid concentrations in grain for CIMMYT’s carotenoid association mapping panel of 380 inbred maize lines, using high-density genome-wide platforms with ~476,000 SNP markers. Population structure effects were minimized by adjustments using principal components and kinship matrix with mixed models. Genome-wide linkage disequilibrium (LD) analysis indicated faster LD decay (3.9 kb; r2 = 0.1) than commonly reported for temperate germplasm, and therefore the possibility of achieving higher mapping resolution with our mostly tropical diversity panel. GWAS for various carotenoids identified CRTRB1, LCYE and other key genes or genomic regions that govern rate-critical steps in the upstream pathway, such as DXS1, GGPS1, and GGPS2 that are known to play important roles in the accumulation of precursor isoprenoids as well as downstream genes HYD5, CCD1, and ZEP1, which are involved in hydroxylation and carotenoid degradation. SNPs at or near all of these regions were identified and may be useful target regions for carotenoid biofortification breeding efforts in maize; for example a genomic region on chromosome 2 explained ~16 % of the phenotypic variance for β-carotene independently of CRTRB1, and a variant of CCD1 that resulted in reduced β-cryptoxanthin degradation was found in lines that have previously been observed to have low proVA degradation rates. |
| 536 ## - FUNDING INFORMATION NOTE |
|---|
| Text of note |
Global Maize Program |
| 536 ## - FUNDING INFORMATION NOTE |
|---|
| Text of note |
Genetic Resources Program |
| 546 ## - LANGUAGE NOTE |
|---|
| Language note |
Text in english |
| 591 ## - CATALOGING NOTES |
|---|
| Number of CIMMYT Informa |
CIMMYT Informa No. 1932 |
| 594 ## - STAFFID |
|---|
| StaffID |
INT1617 |
| 594 ## - STAFFID |
|---|
| StaffID |
INT2691 |
| 594 ## - STAFFID |
|---|
| StaffID |
INT2925 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Maize |
| Miscellaneous information |
AGROVOC |
| Source of heading or term |
|
| 9 (RLIN) |
1173 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| 9 (RLIN) |
1032 |
| Topical term or geographic name as entry element |
Carotenoids |
| Miscellaneous information |
AGROVOC |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| 9 (RLIN) |
1132 |
| Topical term or geographic name as entry element |
Genomics |
| Source of heading or term |
AGROVOC |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| 9 (RLIN) |
143 |
| Personal name |
Kaeppler, S.M. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| 9 (RLIN) |
832 |
| Personal name |
Pixley, K.V. |
| Miscellaneous information |
Genetic Resources Program |
| Field link and sequence number |
INT1617 |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| 9 (RLIN) |
850 |
| Personal name |
Palacios-Rojas, N. |
| Miscellaneous information |
Global Maize Program |
| Field link and sequence number |
INT2691 |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| 9 (RLIN) |
875 |
| Personal name |
BABU, R. |
| Miscellaneous information |
Global Maize Program |
| Field link and sequence number |
INT2925 |
| 773 0# - HOST ITEM ENTRY |
|---|
| Record control number |
u444762 |
| International Standard Serial Number |
1432-2242 (Revista en electrónico) |
| Place, publisher, and date of publication |
Berlin (Germany) : Springer-Verlag Heidelberg |
| Title |
Theoretical and Applied Genetics |
| Related parts |
v. 128, no. 2 |
| 856 4# - ELECTRONIC LOCATION AND ACCESS |
|---|
| Link text |
Open Access through DSpace |
| Uniform Resource Identifier |
http://hdl.handle.net/10883/4563 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
Dewey Decimal Classification |
| Koha item type |
Article |
| Suppress in OPAC |
No |