Knowledge Center Catalog

Metabolome-based genome-wide association study of maize kernel leads to novel biochemical insights (Record no. 30900)

MARC details
000 -LEADER
fixed length control field 02449nab a22004577a 4500
001 - CONTROL NUMBER
control field G99593
003 - CONTROL NUMBER IDENTIFIER
control field MX-TxCIM
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20201201161424.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 121211b |||p||p||||||| |z||| |
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 1476-4687 (Revista en electrónico)
022 0# - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 0028-0836
024 8# - OTHER STANDARD IDENTIFIER
Standard number or code https://doi.org/10.1038/ncomms4438
040 ## - CATALOGING SOURCE
Original cataloging agency MX-TxCIM
041 0# - LANGUAGE CODE
Language code of text/sound track or separate title En
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Weiwei Wen
245 10 - TITLE STATEMENT
Title Metabolome-based genome-wide association study of maize kernel leads to novel biochemical insights
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT)
Date of publication, distribution, etc. 2014
500 ## - GENERAL NOTE
General note Peer-review: Yes - Open Access: Yes | http://ip-science.thomsonreuters.com/cgi-bin/jrnlst/jlresults.cgi?PC=MASTER&ISSN=0028-0836
500 ## - GENERAL NOTE
General note Peer review
500 ## - GENERAL NOTE
General note Open Access
520 ## - SUMMARY, ETC.
Summary, etc. Plants produce a variety of metabolites that have a critical role in growth and development. Here we present a comprehensive study of maize metabolism, combining genetic, metabolite and expression profiling methodologies to dissect the genetic basis of metabolic diversity in maize kernels. We quantify 983 metabolite features in 702 maize genotypes planted at multiple locations. We identify 1,459 significant locus?trait associations (P≤1.8 ? 10−6) across three environments through metabolite-based genome-wide association mapping. Most (58.5%) of the identified loci are supported by expression QTLs, and some (14.7%) are validated through linkage mapping. Re-sequencing and candidate gene association analysis identifies potential causal variants for five candidate genes involved in metabolic traits. Two of these genes were further validated by mutant and transgenic analysis. Metabolite features associated with kernel weight could be used as biomarkers to facilitate genetic improvement of maize.
536 ## - FUNDING INFORMATION NOTE
Text of note Genetic Resources Program
546 ## - LANGUAGE NOTE
Language note English
591 ## - CATALOGING NOTES
Affiliation Nature|CIMMYT Informa No. 1919
594 ## - STAFFID
StaffID CLIH01
595 ## - COLLECTION
Collection CIMMYT Staff Publications Collection
650 10 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Biological Sciences
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Plant sciences
9 (RLIN) 1214
Source of heading or term AGROVOC
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM
9 (RLIN) 1130
Topical term or geographic name as entry element Genetics
Source of heading or term AGROVOC
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM
9 (RLIN) 1853
Topical term or geographic name as entry element Quantitative Trait Loci
Source of heading or term AGROVOC
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM
9 (RLIN) 8948
Topical term or geographic name as entry element Metabolites
Source of heading or term AGROVOC
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Dong Li,
Relator term coaut.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Haijun Liu,
Relator term coaut.
700 1# - ADDED ENTRY--PERSONAL NAME
9 (RLIN) 398
Personal name Jianbing Yan
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Jie Liu,
Relator term coaut.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Jie Luo,
Relator term coaut.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Wei Chen,
Relator term coaut.
9 (RLIN) 2613
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Wenqiang Li,
Relator term coaut.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Xiang Li,
Relator term coaut.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Yanqiang Gao,
Relator term coaut.
700 1# - ADDED ENTRY--PERSONAL NAME
9 (RLIN) 764
Personal name Huihui Li
Miscellaneous information Genetic Resources Program
Field link and sequence number CLIH01
773 0# - HOST ITEM ENTRY
Title Nature
Related parts v. 5, p. 3438
856 4# - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier https://hdl.handle.net/10883/19739
Link text Open Access through DSpace
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Article
Source of classification or shelving scheme Dewey Decimal Classification
Suppress in OPAC No
Holdings
Date last seen Total Checkouts Price effective from Koha item type Lost status Damaged status Not for loan Collection code Withdrawn status Home library Current library Date acquired
07/03/2017   07/03/2017 Article Not Lost     CIMMYT Staff Publications Collection   CIMMYT Knowledge Center: John Woolston Library CIMMYT Knowledge Center: John Woolston Library 07/03/2017

International Maize and Wheat Improvement Center (CIMMYT) © Copyright 2021.
Carretera México-Veracruz. Km. 45, El Batán, Texcoco, México, C.P. 56237.
If you have any question, please contact us at
CIMMYT-Knowledge-Center@cgiar.org