Knowledge Center Catalog

Phenolic composition and mammary cancer cell inhibition of extracts of whole cowpeas (Vigna unguiculata) and its anatomical parts (Record no. 28514)

MARC details
000 -LEADER
fixed length control field 02558nab a22003377a 4500
001 - CONTROL NUMBER
control field G95258
003 - CONTROL NUMBER IDENTIFIER
control field MX-TxCIM
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20171220113531.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 121211b |||p||p||||||| |z||| |
022 0# - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 1756-4646
024 8# - OTHER STANDARD IDENTIFIER
Standard number or code https://doi.org/10.1016/j.jff.2011.05.004
040 ## - CATALOGING SOURCE
Original cataloging agency MX-TxCIM
041 0# - LANGUAGE CODE
Language code of text/sound track or separate title En
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Gutierrez Uribe, J. A.
245 00 - TITLE STATEMENT
Title Phenolic composition and mammary cancer cell inhibition of extracts of whole cowpeas (Vigna unguiculata) and its anatomical parts
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT)
Date of publication, distribution, etc. 2011
500 ## - GENERAL NOTE
General note Please cite this article in press as: Gutierrez-Uribe, J.A. et al., Phenolic composition and mammary cancer cell inhibition of extracts of whole cowpeas (Vigna unguiculata) and its anatomical parts, Journal of Functional Foods (2011), doi:10.1016/j.jff.2011.05.004
520 ## - SUMMARY, ETC.
Summary, etc. The phenolic profile and anticancer properties of extracts from whole cowpeas, seed coats and cotyledons were determined. Seed coats contained at least 5 and 10 times more free and bound phenolics compared to whole seeds (75.6 and 31.7 mg/100 g of free and bound phenolics, respectively). Seed coats and cotyledons contained about 50% and 95% of free phenolics, respectively. The major phenolics associated to seed coats were gallic and protocatechuic acid, whereas in cotyledons p-hydroxybenzoic acid was prevalent. Seed coats contained approximately 10 times more flavonoids compared to whole seeds and cotyledons were practically free of flavonoids. After acid hydrolysis, myricetin, quercetin and kaempferol were identified in seed coats. Most of the antioxidant activity determined with the 2,20-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) and oxygen radical absorbance capacity (ORAC) assays was exerted by free phenolics. The free phenolic extract of whole seeds at a concentration of approximately 100 mg gallic acid equiv. (GAE)/l inhibited 65% the proliferation of hormone-dependent mammary (MCF-7) cancer cells. Extracts of seed coats or cotyledons also inhibited cell proliferation but to a significantly lesser extent, thus indicating synergistic effects between phenolics and other phytochemicals associated to these anatomical parts.
546 ## - LANGUAGE NOTE
Language note English
650 10 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Antioxidants
650 10 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Bound and free phenolics
650 10 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Cancer inhibition
650 10 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Cotyledons
650 10 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Cowpeas
650 10 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Flavonoids
650 10 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Seed coats
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Romo Lopez, I.,
Relator term coaut.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Serna Saldivar, S. O.,
Relator term coaut.
773 0# - HOST ITEM ENTRY
Title Journal of Functional Foods
Related parts p. 1-8
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Article
Source of classification or shelving scheme Dewey Decimal Classification
Holdings
Date last seen Total Checkouts Price effective from Koha item type Lost status Damaged status Not for loan Collection code Withdrawn status Home library Current library Date acquired
07/10/2017   07/10/2017 Article Not Lost     Reprints Collection   CIMMYT Knowledge Center: John Woolston Library CIMMYT Knowledge Center: John Woolston Library 07/10/2017

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