Smith, T.K.

Recent advances in the understanding of Fusarium trichothecene mycotoxicoses - 1992 - Printed

Peer-review: Yes - Open Access: Yes|http://science.thomsonreuters.com/cgi-bin/jrnlst/jlresults.cgi?PC=MASTER&ISSN=0021-8812 references. Paper presented at a symposium entitled "Current Perspectives on Mycotoxins in Animal Feeds," Laramie, WY. Literature review

Recent concepts in the etiology of Fusarium trichothecene mycotoxicoses have been reviewed. The effect of orally administered trichothecenes on tissue metabolism has been traced from the gastrointestinal tract to the liver and subsequently to blood. It is proposed that the hyperaminoacidemia resulting from trichothecene toxicoses contributes to the behavioral changes observed, including loss of appetite and vomiting. Studies with several species and several trichothecenes have shown that elevated brain tryptophan arising from trichothecene-induced aminoacidemia can subsequently alter regional brain serotonin concentrations. This may produce


English

0021-8812


ANIMAL MORPHOLOGY
Central nervous system
Deuteromycotina
Digestive system
Fungi
Miscellaneous animal disorders
Mycotoxins
Nervous system
Toxic substances
Toxins

93-119086
baner

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